In this special episode of DTx Podcast, Eugene is joined by Brent Vaughan, CEO of Cognito, as well as industry leaders from previous episodes, to weigh in on the recent Pear Therapeutics news and the future of prescription digital therapeutics. In this episode, we cover: The impact on the PDT market Future efforts to move DME to PDT The impact on the entrepreneurs currently developing PDT’s Predictions on the future of Pear Therapeutics Reflections on the history and future of DTx from Chris Bergstrom (Amalgam RX), David Klein (Click Therapeutics), Andy Molnar (DTA), Sammeli Liikkanen (Orion), Francesca Wuttke (nen), Andrzej Jonczyk (Prosoma), Steve Driver (Advocate Health) and Grady Hannah (NightWare) Join the HealthXL platform for free today and be the first to read their analysis of Pear’s predicament and what it means for the DTx industry. https://portal-beta.healthxl.com/?s=2fb5 Guest Links and Resources: Connect with Brent Vaughan on LinkedIn Connect with Chris Bergstrom on LinkedIn Connect with David Klein on LinkedIn Connect with Andy Molnar on LinkedIn Connect with Sammeli Liikkanen on LinkedIn Connect with Francesca Wuttke on LinkedIn Connect with Andrzej Jonczyk on LinkedIn Connect with Steve Driver on LinkedIn Connect with Grady Hannah on LinkedIn Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health | Orion Pharma Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Josh Sackman, President and Co-founder of AppliedVR. AppliedVR, in their own words, provide virtual reality-based treatments that represent a comprehensive approach to chronic pain that empowers patients with accessible digital tools self-managed in their own home In this episode, we cover: The origin story of AppliedVR Transitioning from an app store for health VR to focus pain management market Patient experience and the pain management pipeline Funding journey and key funding milestones The scientific hypothesis of "mind over matter" behind AppliedVR's approach and evidence generation journey The FDA approval process for AppliedVR and lessons learned for entrepreneurs. AppliedVR's current business hypothesis and scaling plan Market channels and scaling VR Guest Links and Resources: Connect with Josh Sackman on LinkedIn Visit www.appliedvr.io Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health | Orion Pharma Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Jo Masterson, CEO and Co-Founder of 2Morrow. In their own words 2Morrow's mission is to help millions improve their lives with the use of evidence-based, behavioral change programs. In this episode, we cover: The founding philosophy of 2Morrow and co-founding a company with your partner The funding journey The NIH grant for 2Morrow's program for pain Using a DTx to cope with pain that will not be effected by behaviour change Consumer experience using different 2Morrow programs Core principles of acceptance, awareness and mindfulness Evidence generation and approach to market Guest Links and Resources: Connect with Jo Masterson on LinkedIn Visit www.2morrowinc.com Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health | Orion Pharma Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Brian Wallace, CMO and Co-Founder of Calmsie. Calmsie in their own words are empowering children to develop emotional resilience from an early age. Calmsie creates engaging DTx video games designed to improve outcomes for children with depression and anxiety. In this episode, we cover: Translating addiction science to treat depression and anxiety in children The origin story and funding journey to Calmsie Parent and child experiences using the gamified program Emotional resilience training for prevention of mental health issues How the Calmsie video game affects the brain Evidence generation and deciding on PDT vs non-PDT routes The free workbook helping children understand the war in Ukraine Guest Links and Resources: Connect with Brian Wallace on LinkedIn Visit calmsie.ai Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health | Orion Pharma Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Sylvain Piquet, COO and Co-founder of Five Lives, the app that leverages the new science of brain aging, neuroplasticity, and cognitive reserve to help people improve their brain health and prevent cognitive decline and dementia. In this episode, we cover: The origin story of Five Lives and the motivation behind focusing on dementia and cognitive decline. The demographics benefitting from using Five Lives Gamifying behaviour change Evidence generation and funding journey The advantages of direct-to-consumer distribution through the app store How digital therapeutics can fit within the NHS The challenges of implementing DTx across UK, French, and German markets Guest Links and Resources: Connect with Sylvain Piquet on LinkedIn Visit www.fivelives.health Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health | Orion Pharma Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Hannes Klöpper, CEO of HelloBetter. HelloBetter, in their own words, wants to empower as many people as possible to manage their own mental health and improve their quality of life – anywhere and at any time, without the wait lists. In this episode, we cover: The origin story of HelloBetter, from university research to becoming a digital therapeutic. Structuring a DTx into accessible and consumable courses The patient journey, from receiving a prescription to activating and using the platform. The DiGA process: evidence, benefits and commercialization The reaction of EU vs US investors Guest Links and Resources: Connect with Hannes Klöpper on LinkedIn Visit hellobetter.de Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health | Orion Pharma Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Joe Perekupka, CEO of Freespira. In their own words Freespira is 'the only medication-free, FDA-cleared digital therapeutic treatment proven to significantly reduce or eliminate symptoms of panic disorder, panic attacks and post-traumatic stress disorder in just 28 days.' In this episode, we cover: The founding story of Freespira The user experience from prescription to daily use The role of health coaches within Freespira Identifying potential candidates for Freespira The current landscape for panic disorder treatment and research into MDMA-assisted therapies Evidence generation to FDA approval journey Evolving pricing models The scope of PTSD across the US Guest Links and Resources: Connect with Joseph Perekupka on LinkedIn Visit freespira.com Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Ali Hashemi, Co-founder of meta[bolic]. In their own words, meta[bolic] is a hybrid digital therapeutics company focused on addressing the global metabolic health crisis. In this episode, we cover: The initial business hypothesis of GluCare and meta[bolic] Digital therapeutics vs disease management Why we are becoming more metabolically unstable than previous generations The global metabolic problem Patient experience on the meta[bolic] platform Guest Links and Resources: Connect with Ali Hashemi on LinkedIn Visit Glucare.Health Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram